Inspiratory Deposition Efficiency of Ultrafine Particles in a Human Airway Bifurcation Model
نویسندگان
چکیده
منابع مشابه
Deposition of ultrafine (nano) particles in the human lung.
Increased production of industrial devices constructed with nanostructured materials raises the possibility of environmental and occupational human exposure with consequent adverse health effects. Ultrafine (nano) particles are suspected of having increased toxicity due to their size characteristics that serve as carrier transports. For this reason, it is critical to refine and improve existing...
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Velocity profiles, local deposition efficiencies (DE), and deposition patterns of aerosol particles in the first three generations (i.e., double bifurcations) of an airway model have been simulated numerically, in which the airway model was constructed from computed tomography (CT) scan data of real human tracheobronchial airways. Three steady inhalation conditions, 15, 30, and 60 L/min, were s...
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Efficiency of cloud condensation nuclei formation from ultrafine particles J. R. Pierce and P. J. Adams Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA Department of Civil and Environmental Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA Department of Engineering and Public Policy, Carnegie Mellon University, Pittsburgh, Penns...
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Symmetric airways bifurcation corresponding to generation 12-23 of Weible’s model will be investigated through numerical simulation. Parent’s airway segment is modeled as a smooth circular tube while the child segment is to be considered as asthmatic airway bifurcations. The effect of size of the lumen area and number of folds on particle deposition and pressure drop will be investigated. The p...
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The particle number concentration in ambient air is dominated by nanometer-sized particles. Recent epidemiological studies report an association between the presence of nanoparticles in inhaled air at the workplace and acute morbidity and even mortality in the elderly. A theoretical model of deposition of 20 nm particles in the human alveolus was formulated. Gas flow structure and deposition ra...
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ژورنال
عنوان ژورنال: Aerosol Science and Technology
سال: 2003
ISSN: 0278-6826,1521-7388
DOI: 10.1080/02786820300898